Lactose Intolerance

The “Genetics of metabolism” assay allows detection of a range of genetic polymorphisms associated with metabolic disorders. The employed Real-time PCR method discriminates alleles thus providing genotype information that aids in the evaluation of the genetic background of current clinical conditions or to estimate odds of disease development.

Lactose is a sugar found in milk, constituting about 99 % of all the carbohydrates in milk. Under the influence of lactase in the digestive tract, lactose splits into glucose and galactose, this occurs after these monosaccharides are absorbed. If there is too much undigested lactose in the intestine (activity of the splitting lactase is reduced), and there is sufficient lactic acid bacteria, then the undigested lactose tigers water flow from the body into the bowel cavity, resulting in loose stools (diarrhea), pain, rumbling and bloating. This condition is called lactase deficiency or lactose intolerance.

Lactose Intolerance REAL-TIME PCR Genotyping Kit is intended for detection and allelic discrimination of genetic polymorphisms associated with inherited lactose intolerance.

Indications for genetic analysis:

• Examination of infants with suspected congenital lactase intolerance;

•  Differential diagnosis of lactose intolerance and other gastrointestinal disease in children older than one year and in adults.

Sample: peripheral blood

DNA extraction: PREP-GS-GENETICS and PREP-RAPID-GENETICS kits

Certification: CE/IVD