ParodontoScreen

Microbiocenosis of the oral cavity includes a large number of different types of microorganisms (bacteria, viruses, fungi, protozoa). Qualitative and quantitative balance disruptions between normal microflora forms and opportunistic microorganisms are specific to the dysbiosis state, when an increase in the number of potentially pathogenic microorganisms and/or gain in pathogenic power of some microorganisms are observed

Currently in diagnosing periodontitis the use of traditional methods of clinical and laboratory diagnostics is a common practice. However, etiologically significant pathogens are mainly anaerobes, which significantly complicate diagnostics because of difficulty of anaerobes cultivation under routine laboratory conditions. Moreover, qualified clinical examination should be done with focus on defining an etiological factor of the inflammatory process, which could allow adequate etiologically oriented therapy.

An effective solution in diagnosis of dysbiotic disorders in the oral cavity is ParodontoScreen, the technology for quantitative real-time PCR analysis.

ParodontoScreen REAL-TIME PCR Detection Kit is intended for detection of opportunistic microorganisms inhabiting human oral cavity.

The ParodontoScreen technology allows performing the following tasks within a short time:

• Objectively assess the qualitative and quantitative composition of anaerobic microorganisms simultaneously in different biotopes of the oral cavity;

• Monitor oral hygiene;

• Optimize disease diagnosis at its initial manifestations;

• Conduct differential diagnostics of periodontitis with varying severity of the disease.

Sample: crevicular fluids, dental plaque

DNA extraction: PREP-NA PLUS, PREP-GS PLUS extraction kits

Certification: RUO