Influenza A virus (subtype Н5N1) (RT reagents included)

According to WHO, respiratory tract infections are one of the main causes of sickness rate and mortality both at infancy and at older ages. About 70 % of these infections affect the upper respiratory tract and middle ear region.

Diagnosis and treatment of respiratory infections remain the focus of attention among both therapists and pediatricians since these infections account for over 90 % of all outpatients’ complaints, especially during autumn and winter seasons.

Influenza (flu) is an acute infectious disease of the respiratory tract caused by the influenza virus. It is an acute respiratory viral infection (ARVI). In terms of frequency and number of flu incidences, ARVI ranks first in the world, accounting for 95 % of all infectious diseases. The death rate from this disease remains high: 2 million people in the world die each year from flu.

Influenza viruses belong to the Ortomyxoviridae family, which includes 3 genera: influenza A virus, influenza B virus and influenza C virus. The antigenic properties of internal virion proteins identify influenza virus as genera A, B or C. Further grouping is done according to subtypes of surface proteins hemagglutinin and neuraminidase. Viruses containing three hemagglutinin subtypes (H1, H2, H3) and two neuraminidase subtypes (N1, N2) are of epidemic concern for people.

The features of influenza type A virus genome are associated with a high degree of variability (point mutations, antigenic shift) that causes a variety of subtypes.

The Influenza A virus, subtype H5N1 (avian flu) PCR with reverse transcription Kit is intended for in vitro detection of RNA specific to Influenza A virus subtype H5N1.

Sample: nasal and guttur smears and lavage, tracheal, nasal, pharyngeal, cloacal smears and lavage, as well as fecal and visceral organs samples from dead and diseased animals

DNA extraction: PREP-NA extraction kit

Certification: RUO