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HPV 16,18 Multiplex REAL-TIME PCR Detection Kits

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Human papillomavirus (HPV) belongs to the genus of papilloma viruses of the Papovaviridae family and has a definitive biocycle associated with differentiation of keratinocytes. The virus infects only proliferating epithelial cells of the basal layer. Formation of viral particles occurs in the upper layers of the epithelium. Presently over 100 types of HPV are distinguished, with about 30 of them being able to infect the epithelium of a human urogenital tract.

The most frequently used test for screening of cervical cancer and precancerous changes in the epithelium is a cytological one. At the same time the diagnostic accuracy can vary depending on the specimen collection method, binding technique and smear preparation as well as a researcher’s skills. It is believed that nearly one third of cervical cancer cases are diagnosed in women who were screened regularly during cytological examination and thus false negative results for these patients were obtained. Therefore, DNA diagnostics of HPV infection is currently considered the basis for cervical cancer screening and prevention.

The fact of HPV presence can be used for adjusting an examination plan and frequency of monitoring of pacient. The positive test result has high diagnostic significance for women’s age over 30. DNA diagnosis is used as a confirmatory test when detecting ASC-US (after liquid cytology and visual method) and when monitoring a therapy for CIN II, III.

HPV 16/18 Multiplex REAL-TIME PCR Detection Kit is intended for detection and typing of two most oncogenic and persistent high-risk human papilloma virus types (HPV 16, HPV 18) by method of multiplex Real-Time PCR.

HPV 16,18 is intended for detection and typing of 16 and 18 types of human papilloma virus.

Sample: epithelial cell scrapes from urethra, cervical canal, cervix

DNA extraction: PREP-NA, PREP-GS, PREP-RAPID extraction kits

Certification: CE/IVD

Типы детекции:
Real-time format is designed to detect PCR results during amplification with the help of detecting amplifiers (in real time).