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HLA-DQB1 alleles genotyping Kit

The actual product may vary from the images shown on the website.

The human leukocyte antigen (HLA) is a human histocompatibility gene system – a group of histocompatibility antigens. There are over 150 antigens. The locus is located on chromosome 6; it contains a large number of genes associated with the human immune system.

For diagnostic purposes HLA typing of the DRB1 gene at low resolution or at the level of 13 allele groups are the most commonly used. In most cases, the required level of typing is the allele group: 8 groups for the DQA1 gene and 12 groups for the DQB1 gene.

Genotyping of DRB1 and DQB1 loci at allele group level is used for selecting a potential donor for familial hematopoietic stem cell transplantation as well as for primary screening of a potential donor in non-familial hematopoietic stem cell transplantation.

HLA typing of spouses is used to diagnose causes of reproductive failures to identify similarities in the couple’s HLA gene variants.

HLA-DQB1 REAL-TIME PCR Genotyping Kit is intended for simultaneous detection of 12 alleles and groups of alleles of human major histocompatibility complex DQB1 gene by polymerase chain reaction.

Sample: peripheral blood

DNA extraction: PREP-GS-GENETICS and PREP-RAPID-GENETICS kits

Certification: RU/IVD

Типы детекции:
Real-time format is designed to detect PCR results during amplification with the help of detecting amplifiers (in real time).
RT

Storage requirements

+2...+8° С

Except of minus part of the kit

-18 … -22° С

Shelf life

12 months

Detection instruments

Number of tests

Tubes(ml)/ Strips

Product number

Only DT instruments with 2 and more detection channel

24

not pre-aliquoted (tubes should be ordered separately)

R1-H003-N3/5EU