Streptococcus agalactiae

Group B Streptococcus (GBS) is a part of normal vaginal flora that can be found in 5-35 % of pregnant women. In obstetrics, GBS commonly is associated with infections of urinary tract, chorioamnionitis, puerperal endometritis, bacteriaemia at birth and in postpartum period, premature rupture of membranes and preterm birth. The risk of intranatal infection during vaginal delivery estimated at 50-60 %.

With reference to The American Society for Disease Control (Preventing Early-Onset Group B Strep Disease (GBS), 2016) the risk of infection for fill-term infant is 1-2 %, for preterm infant – 15-20 % and at gestational age less than 28 weeks – 100 %. Moreover, GBS is considered the main cause of newborn sepsis in USA.

GBS diagnostics (in accordance with «Prevention of Perinatal Group B Streptococcal Disease: Revised Guidelines from CDC», 2010):

• At 35-37 weeks gestational age routinely by cultural method with selective medium;

• In case of onset of labor in women with unknown GBS status, the molecular genetic methods are recommended for intranatal research.

The Streptococcus agalactiae REAL-TIME PCR Detection Kit is an in vitro Nucleic Acid Test (NAT) – pathogen-detection-based product.

The Streptococcus agalactiae REAL-TIME PCR Detection Kit is intended for Streptococcus agalactiae (group B streptococcus) DNA detection in human biological samples, washings from catheters and endotracheal tubes and bacterial cultures by real-time PCR.

The Streptococcus agalactiae REAL-TIME PCR Detection Kit can be used in clinical and diagnostic laboratories of medical institutions and research practice.

Certification: RU/IVD